The rainforest (humid tropical Zonobiome) takes up 83% of the protected area, with 502986 hectares including the mountains, whereas the floodable forest (helobiome) takes up 78215 hectares (13%), mainly along the Guayabero river. The bush savannah and rocky vegetation are barely present in the protected area, extending over 24433 hectares south of the mountains, being only 4% of the area.
It is noteworthy that considering the occupation processes undergone by the park, and according to the Corine Land Cover soil covers classification (2012), there is a total intervention for these four biomes of 66960 hectares, with the humid tropical Zonobiome being the most affected (68%), chiefly due to cattle and agricultural activity in areas greater than 50 hectares. The second most affected biome is the Amazon-Orinoquia helobiome with an affectation of 27%.